Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models

Objectives: New drug regimens employing combinations of existing and experimental antimicrobial agents are needed to shorten treatment of tuberculosis (TB) in humans. The spectinamides are narrow-spectrum semisynthetic analogues of spectinomycin, modified to avoid intrinsic efflux by Mycobacterium t...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Antimicrob Chemother
Auteurs principaux: Robertson, Gregory T., Scherman, Michael S., Bruhn, David F., Liu, Jiuyu, Hastings, Courtney, McNeil, Michael R., Butler, Michelle M., Bowlin, Terry L., Lee, Robin B., Lee, Richard E., Lenaerts, Anne J.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400088/
https://ncbi.nlm.nih.gov/pubmed/27999020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw467
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