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An in vitro fluorescence based study of initiation of RNA synthesis by influenza B polymerase

Influenza polymerase replicates, via a complementary RNA intermediate (cRNA), and transcribes the eight viral RNA (vRNA) genome segments. To initiate RNA synthesis it is bound to the conserved 5΄ and 3΄ extremities of the vRNA or cRNA (the ‘promoter’). 5΄-3΄ base-pairing in the distal promoter regio...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Reich, Stefan, Guilligay, Delphine, Cusack, Stephen
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399792/
https://ncbi.nlm.nih.gov/pubmed/28126917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx043
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