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Characterization of PA-N terminal domain of Influenza A polymerase reveals sequence specific RNA cleavage
Influenza virus uses a unique cap-snatching mechanism characterized by hijacking and cleavage of host capped pre-mRNAs, resulting in short capped RNAs, which are used as primers for viral mRNA synthesis. The PA subunit of influenza polymerase carries the endonuclease activity that catalyzes the host...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783182/ https://ncbi.nlm.nih.gov/pubmed/23847103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt603 |
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