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Mycolactone reveals the substrate-driven complexity of Sec61-dependent transmembrane protein biogenesis
Mycolactone is the exotoxin virulence factor produced by Mycobacterium ulcerans, the pathogen responsible for Buruli ulcer. The skin lesions and immunosuppression that are characteristic of this disease result from the action of mycolactone, which targets the Sec61 complex and inhibits the co-transl...
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| 發表在: | J Cell Sci |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Company of Biologists Ltd
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399781/ https://ncbi.nlm.nih.gov/pubmed/28219954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.198655 |
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