Llwytho...

DNA intercalation and cleavage of an antitumor antibiotic dynemicin that contains anthracycline and enediyne cores.

Dynemicin is a hybrid containing anthraquinone and enediyne cores, which contribute to binding and cleavage of DNA, respectively. DNA strand scission by the antitumor antibiotic is significantly enhanced by the addition of NADPH or thiol compounds. The preferential cutting site of dynemicin is on th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sugiura, Y, Shiraki, T, Konishi, M, Oki, T
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1990
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC53997/
https://ncbi.nlm.nih.gov/pubmed/2339123
Tagiau: Ychwanegu Tag
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