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Mycobacterium tuberculosis Cpn60.2 (GroEL2) blocks macrophage apoptosis via interaction with mitochondrial mortalin

Earlier studies suggested that Mycobacterium tuberculosis (Mtb) proteins exported within the host macrophage play an essential role in tuberculosis pathogenesis. In fact, Mtb proteins interact with and deactivate key regulators of many macrophage functions such as phago-lysosome fusion and antigen p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biol Open
Egile Nagusiak: Joseph, Sunil, Yuen, Alex, Singh, Vijender, Hmama, Zakaria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists Ltd 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399554/
https://ncbi.nlm.nih.gov/pubmed/28288970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.023119
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