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Mycobacterium tuberculosis Cpn60.2 (GroEL2) blocks macrophage apoptosis via interaction with mitochondrial mortalin

Earlier studies suggested that Mycobacterium tuberculosis (Mtb) proteins exported within the host macrophage play an essential role in tuberculosis pathogenesis. In fact, Mtb proteins interact with and deactivate key regulators of many macrophage functions such as phago-lysosome fusion and antigen p...

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Detaylı Bibliyografya
Yayımlandı:Biol Open
Asıl Yazarlar: Joseph, Sunil, Yuen, Alex, Singh, Vijender, Hmama, Zakaria
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists Ltd 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399554/
https://ncbi.nlm.nih.gov/pubmed/28288970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.023119
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