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Mycobacterium tuberculosis Cpn60.2 (GroEL2) blocks macrophage apoptosis via interaction with mitochondrial mortalin

Earlier studies suggested that Mycobacterium tuberculosis (Mtb) proteins exported within the host macrophage play an essential role in tuberculosis pathogenesis. In fact, Mtb proteins interact with and deactivate key regulators of many macrophage functions such as phago-lysosome fusion and antigen p...

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Bibliografiske detaljer
Udgivet i:Biol Open
Main Authors: Joseph, Sunil, Yuen, Alex, Singh, Vijender, Hmama, Zakaria
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399554/
https://ncbi.nlm.nih.gov/pubmed/28288970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.023119
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