A Class of Reactive Acyl-CoA Species Reveals the Non-Enzymatic Origins of Protein Acylation

The mechanisms underlying the formation of acyl protein modifications remain poorly understood. By investigating the reactivity of endogenous acyl-CoA metabolites, we found a class of acyl-CoAs that undergoes intramolecular catalysis to form reactive intermediates which non-enzymatically modify prot...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Metab
Autors principals: Wagner, Gregory R., Bhatt, Dhaval P., O’Connell, Thomas M., Thompson, J. Will, Dubois, Laura G., Backos, Donald S., Yang, Hao, Mitchell, Grant A., Ilkayeva, Olga R., Stevens, Robert D., Grimsrud, Paul A., Hirschey, Matthew D.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399522/
https://ncbi.nlm.nih.gov/pubmed/28380375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.03.006
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars