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Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver

Acyl-CoA thioesterase (Acot)2 localizes to the mitochondrial matrix and hydrolyses long-chain fatty acyl-CoA into free FA and CoASH. Acot2 is expressed in highly oxi­dative tissues and is poised to modulate mitochondrial FA oxidation (FAO), yet its biological role is unknown. Using a model of adenov...

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Veröffentlicht in:J Lipid Res
Hauptverfasser: Moffat, Cynthia, Bhatia, Lavesh, Nguyen, Teresa, Lynch, Peter, Wang, Miao, Wang, Dongning, Ilkayeva, Olga R., Han, Xianlin, Hirschey, Matthew D., Claypool, Steven M., Seifert, Erin L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242439/
https://ncbi.nlm.nih.gov/pubmed/25114170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M046961
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