Development of Improved HDAC6 Inhibitors as Pharmacological Therapy for Axonal Charcot–Marie–Tooth Disease

Charcot–Marie–Tooth disease (CMT) is the most common inherited peripheral neuropathy, with an estimated prevalence of 1 in 2500. The degeneration of motor and sensory nerve axons leads to motor and sensory symptoms that progress over time and have an important impact on the daily life of these patie...

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Publicat a:Neurotherapeutics
Autors principals: Benoy, Veronick, Vanden Berghe, Pieter, Jarpe, Matthew, Van Damme, Philip, Robberecht, Wim, Van Den Bosch, Ludo
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398982/
https://ncbi.nlm.nih.gov/pubmed/27957719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-016-0501-z
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