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Bicyclic-Capped Histone Deacetylase 6 Inhibitors with Improved Activity in a Model of Axonal Charcot–Marie–Tooth Disease

Charcot–Marie–Tooth (CMT) disease is a disorder of the peripheral nervous system where progressive degeneration of motor and sensory nerves leads to motor problems and sensory loss and for which no pharmacological treatment is available. Recently, it has been shown in a model for the axonal form of...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Shen, Sida, Benoy, Veronick, Bergman, Joel A., Kalin, Jay H., Frojuello, Mariana, Vistoli, Giulio, Haeck, Wanda, Van Den Bosch, Ludo, Kozikowski, Alan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775085/
https://ncbi.nlm.nih.gov/pubmed/26599234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00286
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