Tauroursodeoxycholic acid (TUDCA) attenuates pressure overload-induced cardiac remodeling by reducing endoplasmic reticulum stress

Pressure overload in the heart induces pathological hypertrophy and is associated with cardiac dysfunction. Apoptosis and fibrosis signaling initiated by the endoplasmic reticulum stress (ERS) is known to contribute to these maladaptive effects. The aim of this study was to investigate whether reduc...

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Publicado en:PLoS One
Main Authors: Rani, Shilpa, Sreenivasaiah, Pradeep Kumar, Kim, Jin Ock, Lee, Mi Young, Kang, Wan Seok, Kim, Yong Sook, Ahn, Youngkeun, Park, Woo Jin, Cho, Chunghee, Kim, Do Han
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398705/
https://ncbi.nlm.nih.gov/pubmed/28426781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176071
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