Tauroursodeoxycholic acid (TUDCA) alleviates endoplasmic reticulum stress of nuclear donor cells under serum starvation

Serum starvation is a routine protocol for synchronizing nuclear donor cells to G0/G1 phase during somatic cell nuclear transfer (SCNT). However, abrupt serum deprivation can cause serious stress to the cells cultured in vitro, which might result in endoplasmic reticulum (ER) stress, chromosome dama...

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Pubblicato in:PLoS One
Autori principali: Zhang, Ying, Qu, Pengxiang, Ma, Xiaonan, Qiao, Fang, Ma, Yefei, Qing, Suzhu, Zhang, Yong, Wang, Yongsheng, Cui, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931650/
https://ncbi.nlm.nih.gov/pubmed/29718981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196785
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