Polyhexamethyleneguanidine Phosphate-Induced Cytotoxicity in Liver Cells Is Alleviated by Tauroursodeoxycholic Acid (TUDCA) via a Reduction in Endoplasmic Reticulum Stress

Polyhexamethyleneguanidine phosphate (PHMG-P) is a widely used polymeric antimicrobial agent known to induce significant pulmonary toxicity. Several studies have reported that the liver also can be a target organ of polyhexamethyleneguanidine (PHMG) toxicity, but the exact effect of this compound on...

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Udgivet i:Cells
Main Authors: Kim, Sou Hyun, Kwon, Doyoung, Lee, Seunghyun, Ki, Sung Hwan, Jeong, Hye Gwang, Hong, Jin Tae, Lee, Yun-Hee, Jung, Young-Suk
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770470/
https://ncbi.nlm.nih.gov/pubmed/31484321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8091023
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