A new model mimicking persistent HBV e antigen-negative infection using covalently closed circular DNA in immunocompetent mice

Despite the availability of an effective vaccine, hepatitis B virus (HBV) infection remains a major health problem. HBV e antigen (HBeAg)-negative strains have become prevalent. Previously, no animal model mimicked the clinical course of HBeAg-negative HBV infection. To establish an HBeAg-negative H...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Wang, Lei, Cao, Min, Wei, Qing Lu, Zhao, Zhong Hua, Xiang, Qin, Wang, Hui Juan, Zhang, Hua Tang, Lai, Guo Qi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398701/
https://ncbi.nlm.nih.gov/pubmed/28426720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175992
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