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A new model mimicking persistent HBV e antigen-negative infection using covalently closed circular DNA in immunocompetent mice
Despite the availability of an effective vaccine, hepatitis B virus (HBV) infection remains a major health problem. HBV e antigen (HBeAg)-negative strains have become prevalent. Previously, no animal model mimicked the clinical course of HBeAg-negative HBV infection. To establish an HBeAg-negative H...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5398701/ https://ncbi.nlm.nih.gov/pubmed/28426720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175992 |
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