Differences in sequences between HBV-relaxed circular DNA and covalently closed circular DNA

The hepatitis B virus (HBV) genome exists in two forms: circular covalently closed DNA (cccDNA) and relaxed circular DNA (RCDNA). Here, we investigated the presence of differences in the sequences of both forms in paired samples of serum and liver tissue. The serum and liver biopsy samples were coll...

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Bibliographische Detailangaben
Veröffentlicht in:Emerg Microbes Infect
Hauptverfasser: Rybicka, Magda, Woziwodzka, Anna, Romanowski, Tomasz, Stalke, Piotr, Dręczewski, Marcin, Bielawski, Krzysztof Piotr
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520316/
https://ncbi.nlm.nih.gov/pubmed/28634352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emi.2017.41
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