Differences in sequences between HBV-relaxed circular DNA and covalently closed circular DNA

The hepatitis B virus (HBV) genome exists in two forms: circular covalently closed DNA (cccDNA) and relaxed circular DNA (RCDNA). Here, we investigated the presence of differences in the sequences of both forms in paired samples of serum and liver tissue. The serum and liver biopsy samples were coll...

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Detalhes bibliográficos
Publicado no:Emerg Microbes Infect
Main Authors: Rybicka, Magda, Woziwodzka, Anna, Romanowski, Tomasz, Stalke, Piotr, Dręczewski, Marcin, Bielawski, Krzysztof Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520316/
https://ncbi.nlm.nih.gov/pubmed/28634352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emi.2017.41
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