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Oncodomains: A protein domain-centric framework for analyzing rare variants in tumor samples

The fight against cancer is hindered by its highly heterogeneous nature. Genome-wide sequencing studies have shown that individual malignancies contain many mutations that range from those commonly found in tumor genomes to rare somatic variants present only in a small fraction of lesions. Such rare...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Peterson, Thomas A., Gauran, Iris Ivy M., Park, Junyong, Park, DoHwan, Kann, Maricel G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398485/
https://ncbi.nlm.nih.gov/pubmed/28426665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005428
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