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A pathway-centric approach to rare variant association analysis

Current endeavours in rare variant analysis are typically underpowered when investigating association signals from individual genes. We undertook an approach to rare variant analysis which utilises biological pathway information to analyse functionally relevant genes together. Conventional filtering...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Richardson, Tom G, Timpson, Nicholas J, Campbell, Colin, Gaunt, Tom R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136291/
https://ncbi.nlm.nih.gov/pubmed/27577545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.113
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