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Incorporating molecular and functional context into the analysis and prioritization of human variants associated with cancer
BACKGROUND AND OBJECTIVE: With recent breakthroughs in high-throughput sequencing, identifying deleterious mutations is one of the key challenges for personalized medicine. At the gene and protein level, it has proven difficult to determine the impact of previously unknown variants. A statistical me...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMJ Group
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277632/ https://ncbi.nlm.nih.gov/pubmed/22319177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2011-000655 |
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