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Domain landscapes of somatic mutations in cancer

BACKGROUND: Large-scale tumor sequencing projects are now underway to identify genetic mutations that drive tumor initiation and development. Most studies take a gene-based approach to identifying driver mutations, highlighting genes mutated in a large percentage of tumor samples as those likely to...

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Detalhes bibliográficos
Main Authors: Nehrt, Nathan L, Peterson, Thomas A, Park, DoHwan, Kann, Maricel G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394412/
https://ncbi.nlm.nih.gov/pubmed/22759657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-S4-S9
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