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Apoptotic and autophagic cell death induced by histone deacetylase inhibitors
Histone deacetylase (HDAC) inhibitors can induce programmed cell death in cancer cells, although the underlying mechanism is obscure. In this study, we show that two distinct HDAC inhibitors, butyrate and suberoylanilide hydroxamic acid (SAHA), induced caspase-3 activation and cell death in multiple...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC539807/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15596714/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0408345102 |
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