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Apoptotic and autophagic cell death induced by histone deacetylase inhibitors

Histone deacetylase (HDAC) inhibitors can induce programmed cell death in cancer cells, although the underlying mechanism is obscure. In this study, we show that two distinct HDAC inhibitors, butyrate and suberoylanilide hydroxamic acid (SAHA), induced caspase-3 activation and cell death in multiple...

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Detalhes bibliográficos
Main Authors: Shao, Yufang, Gao, Zhonghua, Marks, Paul A., Jiang, Xuejun
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539807/
https://ncbi.nlm.nih.gov/pubmed/15596714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408345102
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