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Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death

Autophagy is a cellular catabolic pathway by which long-lived proteins and damaged organelles are targeted for degradation. Activation of autophagy enhances cellular tolerance to various stresses. Recent studies indicate that a class of anticancer agents, histone deacetylase (HDAC) inhibitors, can i...

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Bibliographische Detailangaben
Hauptverfasser: Gammoh, Noor, Lam, Du, Puente, Cindy, Ganley, Ian, Marks, Paul A., Jiang, Xuejun
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340088/
https://ncbi.nlm.nih.gov/pubmed/22493260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204429109
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