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Regulation of inducible nitric oxide synthase by rapid cellular turnover and cotranslational down-regulation by dimerization inhibitors

Overproduction of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) has been implicated in the pathogenesis of many disorders. iNOS is notably distinguished from constitutive NOSs by its production of large amounts of NO for a prolonged period; hence, it was termed the high-output NOS. Und...

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Detalhes bibliográficos
Main Authors: Kolodziejski, Pawel J., Koo, Ja-Seok, Eissa, N. Tony
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539786/
https://ncbi.nlm.nih.gov/pubmed/15601772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406711102
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