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Intracellular formation of ”undisruptable” dimers of inducible nitric oxide synthase
Overproduction of nitric oxide (NO) by inducible NO synthase (iNOS) has been implicated in the pathogenesis of many diseases. iNOS is active only as a homodimer. Dimerization of iNOS represents a potentially critical target for therapeutic intervention. In this study, we show that intracellular iNOS...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC283580/ https://ncbi.nlm.nih.gov/pubmed/14614131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2435290100 |
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