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GAPDH regulates cellular heme insertion into inducible nitric oxide synthase

Heme proteins play essential roles in biology, but little is known about heme transport inside mammalian cells or how heme is inserted into soluble proteins. We recently found that nitric oxide (NO) blocks cells from inserting heme into several proteins, including cytochrome P450s, hemoglobin, NO sy...

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Bibliografiske detaljer
Main Authors: Chakravarti, Ritu, Aulak, Kulwant S., Fox, Paul L., Stuehr, Dennis J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964200/
https://ncbi.nlm.nih.gov/pubmed/20921417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008133107
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