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Hypoxia Directs Human Extravillous Trophoblast Differentiation in a Hypoxia-Inducible Factor–Dependent Manner

Villous cytotrophoblasts are epithelial stem cells of the early human placenta, able to differentiate either into syncytiotrophoblasts in floating chorionic villi or extravillous trophoblasts (EVTs) at the anchoring villi. The signaling pathways regulating differentiation into these two lineages are...

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Détails bibliographiques
Publié dans:Am J Pathol
Auteurs principaux: Wakeland, Anna K., Soncin, Francesca, Moretto-Zita, Matteo, Chang, Ching-Wen, Horii, Mariko, Pizzo, Don, Nelson, Katharine K., Laurent, Louise C., Parast, Mana M.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397702/
https://ncbi.nlm.nih.gov/pubmed/28167044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.11.018
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