Hypoxia Directs Human Extravillous Trophoblast Differentiation in a Hypoxia-Inducible Factor–Dependent Manner

Villous cytotrophoblasts are epithelial stem cells of the early human placenta, able to differentiate either into syncytiotrophoblasts in floating chorionic villi or extravillous trophoblasts (EVTs) at the anchoring villi. The signaling pathways regulating differentiation into these two lineages are...

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Bibliografiske detaljer
Udgivet i:Am J Pathol
Main Authors: Wakeland, Anna K., Soncin, Francesca, Moretto-Zita, Matteo, Chang, Ching-Wen, Horii, Mariko, Pizzo, Don, Nelson, Katharine K., Laurent, Louise C., Parast, Mana M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2017
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397702/
https://ncbi.nlm.nih.gov/pubmed/28167044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.11.018
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