Hypoxia Directs Human Extravillous Trophoblast Differentiation in a Hypoxia-Inducible Factor–Dependent Manner

Villous cytotrophoblasts are epithelial stem cells of the early human placenta, able to differentiate either into syncytiotrophoblasts in floating chorionic villi or extravillous trophoblasts (EVTs) at the anchoring villi. The signaling pathways regulating differentiation into these two lineages are...

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Опубликовано в: :Am J Pathol
Главные авторы: Wakeland, Anna K., Soncin, Francesca, Moretto-Zita, Matteo, Chang, Ching-Wen, Horii, Mariko, Pizzo, Don, Nelson, Katharine K., Laurent, Louise C., Parast, Mana M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2017
Предметы:
Regular Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397702/
https://ncbi.nlm.nih.gov/pubmed/28167044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.11.018
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