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Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease

Trophoblast is the primary epithelial cell type in the placenta, a transient organ required for proper fetal growth and development. Different trophoblast subtypes are responsible for gas/nutrient exchange (syncytiotrophoblasts, STBs) and invasion and maternal vascular remodeling (extravillous troph...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Horii, Mariko, Li, Yingchun, Wakeland, Anna K., Pizzo, Donald P., Nelson, Katharine K., Sabatini, Karen, Laurent, Louise Chang, Liu, Ying, Parast, Mana M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941448/
https://ncbi.nlm.nih.gov/pubmed/27325764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604747113
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