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Hypoxia Directs Human Extravillous Trophoblast Differentiation in a Hypoxia-Inducible Factor–Dependent Manner
Villous cytotrophoblasts are epithelial stem cells of the early human placenta, able to differentiate either into syncytiotrophoblasts in floating chorionic villi or extravillous trophoblasts (EVTs) at the anchoring villi. The signaling pathways regulating differentiation into these two lineages are...
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Veröffentlicht in: | Am J Pathol |
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Hauptverfasser: | , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
American Society for Investigative Pathology
2017
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5397702/ https://ncbi.nlm.nih.gov/pubmed/28167044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.11.018 |
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