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Dexamethasone-Induced Ocular Hypertension in Mice: Effects of Myocilin and Route of Administration

Glucocorticoid (GC)-induced ocular hypertension (OHT) is a serious adverse effect of prolonged GC therapy that can lead to iatrogenic glaucoma and permanent vision loss. An appropriate mouse model can help us understand precise molecular mechanisms and etiology of GC-induced OHT. We therefore develo...

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Publicat a:Am J Pathol
Autors principals: Patel, Gaurang C., Phan, Tien N., Maddineni, Prabhavathi, Kasetti, Ramesh B., Millar, J. Cameron, Clark, Abbot F., Zode, Gulab S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397678/
https://ncbi.nlm.nih.gov/pubmed/28167045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.12.003
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