Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork

Por Kasetti, Ramesh B., Phan, Tien N., Millar, J. Cameron, Zode, Gulab S.
Publicado no Invest Ophthalmol Vis Sci (2016)

Increased synthesis and deposition of extracellular matrix proteins leads to endoplasmic reticulum stress in the trabecular meshwork

Por Kasetti, Ramesh B., Maddineni, Prabhavathi, Millar, J. Cameron, Clark, Abbot F., Zode, Gulab S.
Publicado no Sci Rep (2017)

Transforming growth factor β2 (TGFβ2) signaling plays a key role in glucocorticoid-induced ocular hypertension

Por Kasetti, Ramesh B., Maddineni, Prabhavathi, Patel, Pinkal D., Searby, Charles, Sheffield, Val C., Zode, Gulab S.
Publicado no J Biol Chem (2018)

Dexamethasone-Induced Ocular Hypertension in Mice: Effects of Myocilin and Route of Administration

Por Patel, Gaurang C., Phan, Tien N., Maddineni, Prabhavathi, Kasetti, Ramesh B., Millar, J. Cameron, Clark, Abbot F., Zode, Gulab S.
Publicado no Am J Pathol (2017)

CRISPR-Cas9–based treatment of myocilin-associated glaucoma

Por Jain, Ankur, Zode, Gulab, Kasetti, Ramesh B., Ran, Fei A., Yan, Winston, Sharma, Tasneem P., Bugge, Kevin, Searby, Charles C., Fingert, John H., Zhang, Feng, Clark, Abbot F., Sheffield, Val C.
Publicado no Proc Natl Acad Sci U S A (2017)