Increased synthesis and deposition of extracellular matrix proteins leads to endoplasmic reticulum stress in the trabecular meshwork

Increased synthesis and deposition of extracellular matrix (ECM) proteins in the trabecular meshwork (TM) is associated with TM dysfunction and intraocular pressure (IOP) elevation in glaucoma. However, it is not understood how ECM accumulation leads to TM dysfunction and IOP elevation. Using a mous...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Kasetti, Ramesh B., Maddineni, Prabhavathi, Millar, J. Cameron, Clark, Abbot F., Zode, Gulab S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668243/
https://ncbi.nlm.nih.gov/pubmed/29097767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14938-0
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