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Population Pharmacokinetics and Pharmacodynamics of Benralizumab in Healthy Volunteers and Patients With Asthma

Benralizumab is a humanized, afucosylated, anti‐interleukin‐5 receptor α, immunoglobulin G (IgG) (1) κ monoclonal antibody. We developed a population pharmacokinetic (PK)/pharmacodynamic (PD) model for benralizumab by analyzing PK and blood eosinophil count data from two healthy volunteer studies (N...

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Bibliografiske detaljer
Udgivet i:CPT Pharmacometrics Syst Pharmacol
Main Authors: Wang, B, Yan, L, Yao, Z, Roskos, LK
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397562/
https://ncbi.nlm.nih.gov/pubmed/28109128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12160
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