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Population Pharmacokinetic Modeling of Benralizumab in Adult and Adolescent Patients with Asthma

INTRODUCTION: Benralizumab, an interleukin-5 receptor alpha–directed cytolytic anti-eosinophil monoclonal antibody, was recently approved as add-on maintenance treatment for patients aged 12 years and older with uncontrolled asthma with eosinophilic inflammation. METHODS: Pharmacokinetic (PK) data f...

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Detalhes bibliográficos
Publicado no:Clin Pharmacokinet
Main Authors: Yan, Li, Wang, Bing, Chia, Yen Lin, Roskos, Lorin K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584252/
https://ncbi.nlm.nih.gov/pubmed/30854591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-019-00738-4
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