ロード中...
Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer
P-TEFb (CDK9/cyclin T) plays a central role in androgen receptor (AR)-mediated transactivation by phosphorylating both RNA polymerase 2 complex proteins and AR at S81. CDK9 dephosphorylation mobilizes P-TEFb from an inhibitory 7SK ribonucleoprotein complex, but mechanisms targeting phosphatases to P...
保存先:
| 出版年: | Nucleic Acids Res |
|---|---|
| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2017
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5397168/ https://ncbi.nlm.nih.gov/pubmed/28062857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1291 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|