Protein phosphatase 1 suppresses androgen receptor ubiquitylation and degradation

The phosphoprotein phosphatases are emerging as important androgen receptor (AR) regulators in prostate cancer (PCa). We reported previously that the protein phosphatase 1 catalytic subunit (PP1α) can enhance AR activity by dephosphorylating a site in the AR hinge region (Ser650) and thereby decreas...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Xiaming, Han, Weiwei, Gulla, Sarah, Simon, Nicholas I., Gao, Yanfei, Cai, Changmeng, Yang, Hongmei, Zhang, Xiaoping, Liu, Jihong, Balk, Steven P., Chen, Shaoyong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811495/
https://ncbi.nlm.nih.gov/pubmed/26636645
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