Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells

In human embryonic stem cells (ESCs) the transcription factor Zeb2 regulates neuroectoderm versus mesendoderm formation, but it is unclear how Zeb2 affects the global transcriptional regulatory network in these cell‐fate decisions. We generated Zeb2 knockout (KO) mouse ESCs, subjected them as embryo...

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Detaylı Bibliyografya
Yayımlandı:Stem Cells
Asıl Yazarlar: Stryjewska, Agata, Dries, Ruben, Pieters, Tim, Verstappen, Griet, Conidi, Andrea, Coddens, Kathleen, Francis, Annick, Umans, Lieve, van IJcken, Wilfred F. J., Berx, Geert, van Grunsven, Leo A., Grosveld, Frank G., Goossens, Steven, Haigh, Jody J., Huylebroeck, Danny
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396376/
https://ncbi.nlm.nih.gov/pubmed/27739137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2521
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