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An enhanced recombinant amino‐terminal acetylation system and novel in vivo high‐throughput screen for molecules affecting α‐synuclein oligomerisation

Amino‐terminal acetylation is a ubiquitous protein modification affecting the majority of eukaryote proteins to regulate stability and function. We describe an optimised recombinant expression system for rapid production of amino terminal‐acetylated proteins within bacteria. We go on to describe the...

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Detaylı Bibliyografya
Yayımlandı:FEBS Lett
Asıl Yazarlar: Eastwood, Tara A., Baker, Karen, Brooker, Holly R., Frank, Stefanie, Mulvihill, Daniel P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396276/
https://ncbi.nlm.nih.gov/pubmed/28214355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12597
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