Genotypes of SLC22A4 and SLC22A5 regulatory loci are predictive of the response of chronic myeloid leukemia patients to imatinib treatment

BACKGROUND: Through high-throughput next-generation sequencing of promoters of solute carrier and ATP-binding cassette genes, which encode drug transporters, we aimed to identify SNPs associated with the response to imatinib administered for first-line treatment of patients with chronic myeloid leuk...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Jaruskova, Monika, Curik, Nikola, Hercog, Rajna, Polivkova, Vaclava, Motlova, Eliska, Benes, Vladimir, Klamova, Hana, Pecherkova, Pavla, Belohlavkova, Petra, Vrbacky, Filip, Machova Polakova, Katerina
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395939/
https://ncbi.nlm.nih.gov/pubmed/28420426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0523-3
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