Genotypes of SLC22A4 and SLC22A5 regulatory loci are predictive of the response of chronic myeloid leukemia patients to imatinib treatment

BACKGROUND: Through high-throughput next-generation sequencing of promoters of solute carrier and ATP-binding cassette genes, which encode drug transporters, we aimed to identify SNPs associated with the response to imatinib administered for first-line treatment of patients with chronic myeloid leuk...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Jaruskova, Monika, Curik, Nikola, Hercog, Rajna, Polivkova, Vaclava, Motlova, Eliska, Benes, Vladimir, Klamova, Hana, Pecherkova, Pavla, Belohlavkova, Petra, Vrbacky, Filip, Machova Polakova, Katerina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395939/
https://ncbi.nlm.nih.gov/pubmed/28420426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0523-3
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