Characterization of 46 patient-specific BCR-ABL1 fusions and detection of SNPs upstream and downstream the breakpoints in chronic myeloid leukemia using next generation sequencing

In chronic myeloid leukemia, the identification of individual BCR-ABL1 fusions is required for the development of personalized medicine approach for minimal residual disease monitoring at the DNA level. Next generation sequencing (NGS) of amplicons larger than 1000 bp simplified and accelerated a pr...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Linhartova, Jana, Hovorkova, Lenka, Soverini, Simona, Benesova, Adela, Jaruskova, Monika, Klamova, Hana, Zuna, Jan, Machova Polakova, Katerina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Letter to the Editor
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409993/
https://ncbi.nlm.nih.gov/pubmed/25928096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0363-8
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