Characterization of 46 patient-specific BCR-ABL1 fusions and detection of SNPs upstream and downstream the breakpoints in chronic myeloid leukemia using next generation sequencing

In chronic myeloid leukemia, the identification of individual BCR-ABL1 fusions is required for the development of personalized medicine approach for minimal residual disease monitoring at the DNA level. Next generation sequencing (NGS) of amplicons larger than 1000 bp simplified and accelerated a pr...

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Sparad:
Bibliografiska uppgifter
I publikationen:Mol Cancer
Huvudupphovsmän: Linhartova, Jana, Hovorkova, Lenka, Soverini, Simona, Benesova, Adela, Jaruskova, Monika, Klamova, Hana, Zuna, Jan, Machova Polakova, Katerina
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Letter to the Editor
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409993/
https://ncbi.nlm.nih.gov/pubmed/25928096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0363-8
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