Tau phosphorylation induced by severe closed head traumatic brain injury is linked to the cellular prion protein

Studies in vivo and in vitro have suggested that the mechanism underlying Alzheimer’s disease (AD) neuropathogenesis is initiated by an interaction between the cellular prion protein (PrP(C)) and amyloid-β oligomers (Aβo). This PrP(C)-Aβo complex activates Fyn kinase which, in turn, hyperphosphoryla...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Acta Neuropathol Commun
Glavni autori: Rubenstein, Richard, Chang, Binggong, Grinkina, Natalia, Drummond, Eleanor, Davies, Peter, Ruditzky, Meir, Sharma, Deep, Wang, Kevin, Wisniewski, Thomas
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395835/
https://ncbi.nlm.nih.gov/pubmed/28420443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0435-7
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items