Cell polarity defines three distinct domains in pancreatic β-cells

The structural organisation of pancreatic β-cells in the islets of Langerhans is relatively unknown. Here, using three-dimensional (3D) two-photon, 3D confocal and 3D block-face serial electron microscopy, we demonstrate a consistent in situ polarisation of β-cells and define three distinct cell sur...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Gan, Wan J., Zavortink, Michael, Ludick, Christine, Templin, Rachel, Webb, Robyn, Webb, Richard, Ma, Wei, Poronnik, Philip, Parton, Robert G., Gaisano, Herbert Y., Shewan, Annette M., Thorn, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394774/
https://ncbi.nlm.nih.gov/pubmed/26919978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.185116
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