Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell

AIMS/HYPOTHESIS: In dispersed single beta cells the response of each cell to glucose is heterogeneous. In contrast, within an islet, cell-to-cell communication leads to glucose inducing a more homogeneous response. For example, increases in NAD(P)H and calcium are relatively uniform across the cells...

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Hauptverfasser: Low, Jiun T., Mitchell, Justin M., Do, Oanh H., Bax, Jacinda, Rawlings, Alicia, Zavortink, Michael, Morgan, Garry, Parton, Robert G., Gaisano, Herbert Y., Thorn, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825531/
https://ncbi.nlm.nih.gov/pubmed/23995471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-013-3019-5
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