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Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell
AIMS/HYPOTHESIS: In dispersed single beta cells the response of each cell to glucose is heterogeneous. In contrast, within an islet, cell-to-cell communication leads to glucose inducing a more homogeneous response. For example, increases in NAD(P)H and calcium are relatively uniform across the cells...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Springer Berlin Heidelberg
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3825531/ https://ncbi.nlm.nih.gov/pubmed/23995471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-013-3019-5 |
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