Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis

The metastatic organotropism has been one of the cancer's greatest mysteries since the ‘seed and soil' hypothesis. Although the role of EGFR in cancer cells is well studied, the effects of secreted EGFR transported by exosomes are less understood. Here we show that EGFR in exosomes secrete...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Zhang, Haiyang, Deng, Ting, Liu, Rui, Bai, Ming, Zhou, Likun, Wang, Xia, Li, Shuang, Wang, Xinyi, Yang, Haiou, Li, Jialu, Ning, Tao, Huang, Dingzhi, Li, Hongli, Zhang, Le, Ying, Guoguang, Ba, Yi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394240/
https://ncbi.nlm.nih.gov/pubmed/28393839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15016
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia