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Controversy about pharmacological modulation of Nrf2 for cancer therapy

Conventional anticancer therapies such as radiotherapy and chemotherapies are associated with oxidative stress generating reactive oxygen species (ROS) and reactive aldehydes like 4-hydroxynonenal in cancer cells that govern them to die. The main mechanism activated due to exposure of the cell to th...

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Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: Milkovic, Lidija, Zarkovic, Neven, Saso, Luciano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393166/
https://ncbi.nlm.nih.gov/pubmed/28411557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.04.013
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