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Controversy about pharmacological modulation of Nrf2 for cancer therapy

Conventional anticancer therapies such as radiotherapy and chemotherapies are associated with oxidative stress generating reactive oxygen species (ROS) and reactive aldehydes like 4-hydroxynonenal in cancer cells that govern them to die. The main mechanism activated due to exposure of the cell to th...

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Podrobná bibliografie
Vydáno v:Redox Biol
Hlavní autoři: Milkovic, Lidija, Zarkovic, Neven, Saso, Luciano
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393166/
https://ncbi.nlm.nih.gov/pubmed/28411557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.04.013
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